Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126898 | 0.85 | TRPV1 (0.41) | MALT1NPC1RAB9ATRPV1PSEN1 | |
| SCHEMBL1993791 | 0.79 | TRPV1 (0.38) | NPC1RAB9ATRPV1TSHRMAPT | |
| SCHEMBL1126932 | 0.77 | MAPT (0.38) | MALT1NPC1RAB9ATRPV1TSHR | |
| SCHEMBL1127445 | 0.77 | TRPV1 (0.39) | MALT1TRPV1TSHRPSEN1PSEN2 | |
| SCHEMBL1126527 | 0.76 | MAPT (0.37) | TRPV1TSHRPSEN1PSEN2APH1B | |
| SCHEMBL1127448 | 0.75 | ALDH1A1 (0.39) | MALT1TRPV1TSHRMAPTALDH1A1 | |
| SCHEMBL1647342 | 0.74 | MAPT (0.40) | MALT1NPC1RAB9ATRPV1PSEN1 | |
| SCHEMBL1127185 | 0.74 | MALT1 (0.37) | MALT1NPC1RAB9ATRPV1TSHR | |
| SCHEMBL1127265 | 0.74 | KDR (0.37) | MALT1TRPV1TSHRPSEN1PSEN2 | |
| SCHEMBL1127332 | 0.74 | MCHR1 (0.39) | MALT1NPC1RAB9ATRPV1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |