Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 7/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261043 | 0.86 | HDAC1 (0.39) | ALDH1A1LMNATP53 | |
| SCHEMBL11254401 | 0.83 | NPC1 (0.44) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL11269178 | 0.76 | DRD2 (0.38) | ALDH1A1LMNADRD2RAD52 | |
| SCHEMBL11268503 | 0.75 | DRD2 (0.39) | ALDH1A1TSHRDRD2ABL1RAD52 | |
| SCHEMBL7343072 | 0.73 | CACNA2D1 (0.53) | ALDH1A1LMNATP53CACNA2D1CACNA1B | |
| SCHEMBL11252945 | 0.71 | DRD2 (0.48) | ALDH1A1TP53TSHRDRD2ABL1 | |
| SCHEMBL209154 | 0.69 | DRD4 (0.61) | ALDH1A1LMNACACNA2D1CACNA1BCACNB1 | |
| SCHEMBL11251039 | 0.69 | CLK1 (0.57) | ALDH1A1TSHRHTT | |
| SCHEMBL11267504 | 0.68 | DRD2 (0.41) | ALDH1A1LMNATSHRHTTNPSR1 | |
| SCHEMBL4559554 | 0.67 | DRD4 (0.43) | ALDH1A1LMNATP53CACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |