Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252945 | 0.94 | DRD2 (0.48) | DRD2SIGMAR1NPC1RAB9AABL1 | |
| SCHEMBL11269178 | 0.75 | DRD2 (0.38) | DRD2SIGMAR1NPC1RAB9AMEN1 | |
| SCHEMBL11270284 | 0.75 | ALDH1A1 (0.43) | DRD2ABL1ALDH1A1TSHRRAD52 | |
| SCHEMBL11254401 | 0.74 | NPC1 (0.44) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL11257322 | 0.70 | DRD2 (0.40) | DRD2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL11261043 | 0.69 | HDAC1 (0.39) | SIGMAR1MAPTALDH1A1HTR2C | |
| SCHEMBL11251027 | 0.69 | HTR2C (0.39) | DRD2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11251039 | 0.68 | CLK1 (0.57) | CLK1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL11267504 | 0.67 | DRD2 (0.41) | DRD2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL11268499 | 0.63 | CLK1 (0.62) | CLK1KDM4EALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |