Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270284 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNATP53 | |
| SCHEMBL11269178 | 0.76 | DRD2 (0.38) | ALDH1A1HTR2CSIGMAR1S1PR1LMNA | |
| SCHEMBL11254401 | 0.73 | NPC1 (0.44) | ALDH1A1MAPTLMNATP53 | |
| SCHEMBL11268503 | 0.69 | DRD2 (0.39) | ALDH1A1HTR2CSIGMAR1MAPT | |
| SCHEMBL7348001 | 0.69 | HDAC1 (0.53) | HDAC1HDAC8HDAC6ALDH1A1MAPT | |
| SCHEMBL7348767 | 0.65 | HDAC1 (0.50) | HDAC1HDAC8HDAC6ALDH1A1SLC6A2 | |
| SCHEMBL11252945 | 0.65 | DRD2 (0.48) | ALDH1A1SIGMAR1KCNH2TP53 | |
| SCHEMBL11261033 | 0.64 | CSNK1D (0.48) | MAPTCSNK1D | |
| SCHEMBL11261037 | 0.64 | MAPT (0.64) | ALDH1A1MAPTLMNACSNK1D | |
| SCHEMBL20376806 | 0.64 | CSNK1D (0.51) | CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |