Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 3/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254401 | 0.81 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11261043 | 0.76 | HDAC1 (0.39) | HTR2CSIGMAR1ALDH1A1LMNAS1PR1 | |
| SCHEMBL11270284 | 0.76 | ALDH1A1 (0.43) | DRD2RAD52ALDH1A1LMNA | |
| SCHEMBL11268503 | 0.75 | DRD2 (0.39) | DRD2NPC1RAB9ARAD52HTR2C | |
| SCHEMBL11252945 | 0.71 | DRD2 (0.48) | DRD2NPC1RAB9AHSD17B10SIGMAR1 | |
| SCHEMBL11251039 | 0.69 | CLK1 (0.57) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11267504 | 0.68 | DRD2 (0.41) | DRD2NPC1RAB9ARAD52HTR2C | |
| SCHEMBL11251027 | 0.67 | HTR2C (0.39) | DRD2NPC1RAB9ARAD52SCN4A | |
| SCHEMBL11269176 | 0.61 | CLK1 (0.56) | SLC27A1MEN1KMT2AALDH1A1 | |
| SCHEMBL11255745 | 0.61 | HTR2C (0.41) | NPC1RAB9ARAD52HTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |