Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12019676 | 0.78 | POLB (0.46) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11266362 | 0.78 | CASP1 (0.42) | POLBNR1H2ALDH1A1MEN1CASP1 | |
| SCHEMBL1926995 | 0.71 | ALDH1A1 (0.49) | GAAGLAPOLBTSHRNR1H2 | |
| SCHEMBL11263789 | 0.71 | NR1H2 (0.45) | GAAGLAPOLBTSHRNR1H2 | |
| SCHEMBL10915573 | 0.69 | ALDH1A1 (0.56) | GAAGLAPOLBTSHRNR1H2 | |
| SCHEMBL6140218 | 0.69 | GAA (0.47) | GAAGLAPOLBTSHRNR1H2 | |
| SCHEMBL4540644 | 0.69 | POLB (0.47) | GAAGLAPOLBTSHRNR1H2 | |
| SCHEMBL4544013 | 0.68 | LDHA (0.40) | GAAGLAPOLBTSHRALDH1A1 | |
| SCHEMBL29959068 | 0.68 | MAPT (0.59) | GAAGLAPOLBTSHRNR1H2 | |
| SCHEMBL880662 | 0.68 | MAPT (0.59) | GAAGLAPOLBTSHRNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003619-B1 | HETEROCYCLIC-SUBSTITUTED ANILIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND A METHOD OF CONTROLLING UNDESIRED PLANT GROWTH USING THEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-05-05 | — | — | EP | disclosed |
| EP-0003619-A2 | Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-08-22 | — | — | EP | disclosed |