Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126441 | 0.79 | TSHR (0.38) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1127950 | 0.71 | MAPT (0.35) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1126771 | 0.68 | GFER (0.37) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1126854 | 0.67 | GFER (0.39) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1126589 | 0.67 | LMNA (0.39) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL15163665 | 0.67 | ADORA2A (0.32) | TSHRSMN1; SMN2 | |
| SCHEMBL1127551 | 0.65 | NPC1 (0.37) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1126437 | 0.63 | TSHR (0.37) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1126557 | 0.63 | LMNA (0.39) | TSHRRGS12SMN1; SMN2GFER | |
| SCHEMBL1987403 | 0.61 | ALDH1A1 (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |