SCHEMBL1126437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127950	0.89	MAPT (0.35)	TSHRF10GFERSMN1; SMN2RGS12
	SCHEMBL1127550	0.87	TSHR (0.37)	TSHRF10GFERSMN1; SMN2RGS12
	SCHEMBL1126674	0.86	LMNA (0.38)	TSHRF10NPC1RAB9AUSP2
	SCHEMBL1988133	0.85	DRD2 (0.39)	TSHRF10GFERSMN1; SMN2RGS12
	SCHEMBL1126519	0.84	F10 (0.41)	TSHRF10SMN1; SMN2NPC1RAB9A
	SCHEMBL1126559	0.84	MAPT (0.38)	TSHRF10SMN1; SMN2NPC1RAB9A
	SCHEMBL1127517	0.84	RAB9A (0.41)	TSHRF10SMN1; SMN2NPC1RAB9A
	SCHEMBL1126697	0.83	MALT1 (0.41)	TSHRF10NPC1RAB9AALDH1A1
	SCHEMBL1993791	0.81	TRPV1 (0.38)	TSHRF10SMN1; SMN2RGS12TRPV1
	SCHEMBL1987514	0.81	NPY2R (0.38)	TSHRNPC1RAB9AUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.