SCHEMBL1127950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126441	0.90	TSHR (0.38)	MAPTTSHRNPSR1F10GFER
	SCHEMBL1126437	0.89	TSHR (0.37)	MAPTTSHRNPSR1F10GFER
	SCHEMBL16500315	0.86	RAB9A (0.37)	MAPTTSHRNPSR1GFERSMN1; SMN2
	SCHEMBL1126674	0.84	LMNA (0.38)	MAPTTSHRF10NPC1RAB9A
	SCHEMBL1126519	0.83	F10 (0.41)	MAPTTSHRF10SMN1; SMN2NPC1
	SCHEMBL1126559	0.82	MAPT (0.38)	MAPTTSHRF10SMN1; SMN2NPC1
	SCHEMBL1127517	0.82	RAB9A (0.41)	MAPTTSHRNPSR1F10SMN1; SMN2
	SCHEMBL1988133	0.82	DRD2 (0.39)	MAPTTSHRF10GFERSMN1; SMN2
	SCHEMBL1126697	0.81	MALT1 (0.41)	MAPTTSHRF10NPC1RAB9A
	SCHEMBL1127550	0.81	TSHR (0.37)	MAPTTSHRNPSR1F10GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.