Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275323 | 0.87 | GPR35 (0.33) | PKMGPR35MAPTPOLBMEN1 | |
| SCHEMBL11285888 | 0.86 | POLB (0.40) | MAPTPOLBNPC1RAB9ALMNA | |
| SCHEMBL11273550 | 0.85 | MAPT (0.39) | EGFRGPR35MAPTPOLB | |
| SCHEMBL11284580 | 0.84 | CSNK2A2 (0.39) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL11276735 | 0.79 | GPR35 (0.47) | PKMEGFRSRCGPR35MAPT | |
| SCHEMBL11270977 | 0.73 | MAPT (0.40) | MAPTPOLBMEN1KMT2ALMNA | |
| SCHEMBL11558528 | 0.67 | CYP3A4 (0.51) | PKMEGFRSRCMAPTPOLB | |
| SCHEMBL11559483 | 0.67 | MEN1 (0.52) | PKMEGFRSRCMAPTNPC1 | |
| SCHEMBL10370941 | 0.67 | MPO (0.51) | MAPTAPOBEC3GPOLBNPC1RAB9A | |
| SCHEMBL11074319 | 0.66 | CSNK2A2 (0.59) | MAPTPOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |