Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285888 | 0.90 | POLB (0.40) | MAPTPOLBTP53THRB | |
| SCHEMBL11284580 | 0.87 | CSNK2A2 (0.39) | MAPTPOLBTP53THRB | |
| SCHEMBL11269598 | 0.85 | PKM (0.41) | MAPTPOLBGPR35EGFR | |
| SCHEMBL11270041 | 0.77 | ALDH1A1 (0.53) | GPR35EGFRMAOB | |
| SCHEMBL11273764 | 0.77 | PLK1 (0.33) | MAPTPLK1 | |
| SCHEMBL11270977 | 0.76 | MAPT (0.40) | MAPTPOLBTHRB | |
| SCHEMBL11275323 | 0.75 | GPR35 (0.33) | MAPTPOLBGPR35 | |
| SCHEMBL11416700 | 0.72 | MAOB (0.61) | MAPTPOLBTP53GPR35MAOB | |
| SCHEMBL11074319 | 0.69 | CSNK2A2 (0.59) | MAPTPOLBMAOB | |
| SCHEMBL10654943 | 0.67 | KDM4E (0.36) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |