Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285888 | 0.88 | POLB (0.40) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL11273550 | 0.87 | MAPT (0.39) | MAPTPOLBTHRBTP53 | |
| SCHEMBL11270977 | 0.87 | MAPT (0.40) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL11269598 | 0.84 | PKM (0.41) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10654943 | 0.79 | KDM4E (0.36) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11275323 | 0.78 | GPR35 (0.33) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11074319 | 0.77 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL11283760 | 0.76 | ALDH1A1 (0.36) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11278189 | 0.75 | KDM4E (0.50) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ALDH1A1 | |
| SCHEMBL11269004 | 0.74 | EGFR (0.43) | CSNK2A2CSNK2BCSNK2A1CSNK2A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |