Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127241 | 0.80 | RPA1 (0.43) | KDM4EALDH1A1HPGDRPA1MCL1 | |
| SCHEMBL1127505 | 0.69 | RPA1 (0.54) | KDM4EALDH1A1HPGDRPA1MCL1 | |
| SCHEMBL1126895 | 0.65 | MTNR1A (0.39) | MTNR1AMTNR1BCYP1A2GAACYP2C9 | |
| SCHEMBL15798360 | 0.65 | MAPT (0.44) | MAPT | |
| SCHEMBL28735087 | 0.64 | SIGMAR1 (0.52) | MTNR1AMTNR1BPPARGPPARALTA4H | |
| SCHEMBL11502513 | 0.64 | MTNR1A (0.56) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL1418060 | 0.63 | MTNR1A (0.59) | MTNR1AMTNR1BALDH1A1HPGDMEN1 | |
| SCHEMBL11364006 | 0.62 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGFERGAA | |
| Acetic Acid SCHEMBL27633889 | 0.62 | MTNR1A (0.62) | MTNR1AMTNR1BCYP1A2GAACYP2C9 | |
| SCHEMBL22402775 | 0.62 | MCL1 (0.40) | MCL1CYP1A2CYP2C9PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |