Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.37 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127126 | 0.80 | MTNR1A (0.41) | RPA1MCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL1127505 | 0.70 | RPA1 (0.54) | RPA1MCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL15798360 | 0.69 | MAPT (0.44) | MAPT | |
| SCHEMBL11364006 | 0.64 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDGFERFABP3 | |
| SCHEMBL1127401 | 0.63 | CD274 (0.33) | HPGDMEN1KMT2AMAPTLMNA | |
| SCHEMBL18919750 | 0.63 | MCL1 (0.68) | RPA1MCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL10989712 | 0.62 | KDM4E (0.50) | RPA1MCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL15798540 | 0.62 | MAPT (0.43) | ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL9863296 | 0.61 | FBP1 (0.40) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL5821110 | 0.61 | KDM4E (0.44) | RPA1MCL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |