Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.33 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.33 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016516 | 0.82 | NPSR1 (0.35) | LMNAMAPTNPSR1KMT2AMAOB | |
| SCHEMBL11272047 | 0.79 | NPSR1 (0.43) | LMNAMAPTMAPK1NPSR1KMT2A | |
| SCHEMBL11297976 | 0.77 | MAPT (0.41) | LMNAMAPTABCB11MAPK1RAB9A | |
| SCHEMBL11299822 | 0.76 | ABCB11 (0.42) | LMNAMAPTABCB11MAPK1RAB9A | |
| SCHEMBL11272688 | 0.73 | ABCB11 (0.52) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11269019 | 0.72 | ABCB11 (0.48) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11071353 | 0.72 | ABCB11 (0.38) | LMNAMAPTABCB11MAPK1 | |
| SCHEMBL11080432 | 0.72 | SPHK1 (0.36) | LMNAMAPTABCB11MAPK1 | |
| SCHEMBL7578766 | 0.72 | LMNA (0.60) | LMNAMAPTABCB11MAPK1KMT2A | |
| SCHEMBL11289727 | 0.72 | ABCB11 (0.73) | LMNAMAPTABCB11MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |