Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ESRRB | O95718 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLD2 | O14939 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276906 | 0.90 | CHRNB2 (0.57) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL11438620 | 0.88 | CHRNB2 (0.58) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL11275931 | 0.88 | TSHR (0.53) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL12212607 | 0.81 | KDM4E (0.59) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL10346703 | 0.81 | ALDH1A1 (0.63) | LMNAMAPK1ESR1POLBHIF1A | |
| SCHEMBL10838063 | 0.80 | HIF1A (0.51) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL15296872 | 0.79 | POLB (0.53) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL10836817 | 0.78 | LMNA (0.49) | LMNAKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL6264190 | 0.76 | HIF1A (0.57) | LMNAKDM4EPOLBHIF1AALDH1A1 | |
| SCHEMBL23074660 | 0.76 | KCNH2 (0.54) | LMNAKDM4EMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064487-A1 | New substituted 3-(parasubstituted)phenoxy-1-alkylamino-propanol-2-s, as well as process for their preparation, pharmaceutical preparations containing same, and method for treating cardiac failure | Aktiebolaget Hässle (SE) | 1982-11-10 | — | — | EP | disclosed |