Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10275655 | 0.72 | ALDH1A1 (0.46) | CYP2D6CYP2C9CYP2C19PIN1 | |
| SCHEMBL11269036 | 0.72 | MMP8 (0.46) | PIN1 | |
| SCHEMBL8906464 | 0.69 | PIN1 (0.39) | HTTATML3MBTL1PIN1 | |
| SCHEMBL10028356 | 0.69 | MAPT (0.40) | CYP2C9CYP2C19L3MBTL1PIN1 | |
| SCHEMBL11274448 | 0.68 | PIN1 (0.33) | L3MBTL1METAP2PIN1 | |
| SCHEMBL6070239 | 0.67 | ALDH1A1 (0.44) | CYP2D6CYP2C9CYP2C19PIN1 | |
| SCHEMBL28265249 | 0.66 | PIN1 (0.37) | HTTATML3MBTL1PIN1 | |
| SCHEMBL5972394 | 0.66 | MEN1 (0.40) | CYP2C9CYP2C19HTTPIN1 | |
| SCHEMBL15474317 | 0.65 | ALDH1A1 (0.39) | CYP2D6CYP2C9CYP2C19PIN1 | |
| SCHEMBL17111315 | 0.65 | ALDH1A1 (0.38) | PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |