Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250722 | 0.76 | SLC9A1 (0.38) | CYP1A2SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL9527213 | 0.76 | LMNA (0.31) | TSHRLMNAMAPK1 | |
| SCHEMBL11709141 | 0.76 | LMNA (0.31) | TSHRLMNAMAPK1 | |
| SCHEMBL11389444 | 0.76 | MAPT (0.33) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11276030 | 0.75 | MAOB (0.34) | ATMMEN1KMT2AMAOB | |
| SCHEMBL3523519 | 0.73 | LMNA (0.39) | TSHRLMNAGAAKDM4EHSD17B10 | |
| SCHEMBL8423726 | 0.72 | — | — | |
| SCHEMBL11868744 | 0.72 | MAPT (0.38) | LMNAGAAKDM4EMEN1MAPK1 | |
| SCHEMBL6610178 | 0.70 | LMNA (0.40) | TSHRSMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL11020384 | 0.70 | SIGMAR1 (0.39) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |