Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814714 | 0.98 | HTR7 (0.57) | HTR7DRD1DRD3ABCB1SIGMAR1 | |
| SCHEMBL11280944 | 0.97 | HTR7 (0.60) | HTR7DRD1DRD3ABCB1SIGMAR1 | |
| SCHEMBL11279021 | 0.90 | S1PR5 (0.55) | HTR7DRD1DRD3ABCB1SIGMAR1 | |
| SCHEMBL11276751 | 0.87 | HTR7 (0.58) | HTR7DRD1DRD3ABCB1SIGMAR1 | |
| SCHEMBL11262308 | 0.87 | SLC6A2 (0.56) | HTR7DRD3ABCB1HTR2ADRD2 | |
| SCHEMBL11275248 | 0.86 | HTR1A (0.50) | HTR7DRD1DRD3ABCB1SIGMAR1 | |
| SCHEMBL11284128 | 0.86 | HTR7 (0.59) | HTR7DRD1DRD3ABCB1SIGMAR1 | |
| SCHEMBL11279326 | 0.85 | HTR1A (0.63) | DRD3SIGMAR1HTR2ADRD2 | |
| SCHEMBL11276199 | 0.84 | KCNH2 (0.58) | HTR7DRD3ABCB1SIGMAR1HTR2A | |
| SCHEMBL11276677 | 0.83 | KCNH2 (0.61) | HTR7DRD1DRD3ABCB1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |