Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15162338 | 0.87 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL1993379 | 0.85 | GABRA1 (0.40) | KDM4EALDH1A1GAAGABRA1GABRG2 | |
| SCHEMBL15162319 | 0.80 | THRB (0.36) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL15161896 | 0.68 | CNR1 (0.38) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL1127378 | 0.65 | HPGD (0.41) | ALDH1A1HSD17B10GAASMN1; SMN2MAPT | |
| SCHEMBL1126904 | 0.64 | PPARG (0.35) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL1127123 | 0.64 | ALDH1A1 (0.40) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1126951 | 0.63 | CASR (0.39) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL24584645 | 0.63 | PGR (0.43) | KDM4EALDH1A1GAAMEN1GLA | |
| SCHEMBL31585967 | 0.63 | SMN1; SMN2 (0.39) | ALDH1A1HSD17B10MEN1KMT2AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |