SCHEMBL1126904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15161873	0.89	THRB (0.37)	ARSMN1; SMN2KDM4EGAAALDH1A1
	SCHEMBL1127378	0.88	HPGD (0.41)	SMN1; SMN2TP53GAAALDH1A1MITF
	SCHEMBL1127195	0.87	RARB (0.39)	PPARGARKDM4EGAATSHR
	SCHEMBL1127423	0.87	TSHR (0.39)	ARMEN1KMT2ASMN1; SMN2KDM4E
	SCHEMBL1127780	0.86	KDM4E (0.39)	KMT2AKDM4ETP53GAAALDH1A1
	SCHEMBL1126775	0.85	ALDH1A1 (0.40)	KMT2AKDM4ETP53GAAALDH1A1
	SCHEMBL1126938	0.81	KDM4E (0.43)	MEN1KMT2ASMN1; SMN2KDM4EGAA
	SCHEMBL1127235	0.80	THRB (0.37)	ARMEN1KMT2ASMN1; SMN2KDM4E
	SCHEMBL23488097	0.80	THRB (0.40)	ARMEN1KMT2ASMN1; SMN2KDM4E
	SCHEMBL15161860	0.80	LMNA (0.44)	MEN1KMT2ASMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.