SCHEMBL1993379

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127705	0.85	KDM4E (0.36)	GABRA1GABRG2GABRB3GABRA3ASH1L
	SCHEMBL16500197	0.73	ALDH1A1 (0.44)	GABRA1GABRG2GABRB3GABRA3KDM4E
	SCHEMBL1127204	0.72	THRB (0.40)	GABRA1GABRG2GABRB3GABRA3THRB
	SCHEMBL15162338	0.72	ALDH1A1 (0.43)	THRBKDM4ESMN1; SMN2CYP2C19L3MBTL1
	SCHEMBL24584645	0.72	PGR (0.43)	KDM4ESMN1; SMN2L3MBTL1ALDH1A1GAA
	SCHEMBL1126650	0.70	THRB (0.41)	GABRA1GABRG2GABRB3GABRA3THRB
	SCHEMBL31585967	0.69	SMN1; SMN2 (0.39)	GABRA1GABRG2GABRB3GABRA3THRB
	SCHEMBL15161896	0.69	CNR1 (0.38)	GABRA1GABRG2GABRB3GABRA3THRB
	SCHEMBL31585835	0.68	GABRA1 (0.45)	GABRA1GABRG2GABRB3GABRA3THRB
	SCHEMBL15162319	0.67	THRB (0.36)	GABRA1GABRG2GABRB3GABRA3THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.