Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127466 | 0.76 | HTT (0.41) | HTTALDH1A1NEK1SGK1CAMKK2 | |
| SCHEMBL1126705 | 0.75 | HTT (0.50) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL16007019 | 0.72 | HTT (0.54) | HTTALDH1A1HPGDNEK1SGK1 | |
| SCHEMBL16112588 | 0.70 | HTT (0.52) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL9805097 | 0.70 | HTT (1.00) | HTTALDH1A1HPGDNEK1SGK1 | |
| SCHEMBL27395864 | 0.69 | ALDH1A1 (0.79) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL1126776 | 0.69 | ALDH1A1 (0.53) | HTTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL16111747 | 0.69 | LMNA (0.48) | HTTALDH1A1HPGDHSD17B10NEK1 | |
| SCHEMBL5769402 | 0.69 | CA12 (0.44) | HTTALDH1A1SGK1CAMKK2KMT2A | |
| SCHEMBL26553256 | 0.69 | LMNA (0.48) | HTTALDH1A1AXLNR4A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |