Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | BPTF | Q12830 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281409 | 0.88 | PYGL (0.44) | HTTSMN1; SMN2NPSR1ALDH1A1MITF | |
| SCHEMBL11278901 | 0.84 | HTT (0.46) | ITGB1ITGA4ITGB7HTTSMN1; SMN2 | |
| SCHEMBL11273766 | 0.78 | SMN1; SMN2 (0.47) | ITGB1ITGA4ITGB7HTTSMN1; SMN2 | |
| SCHEMBL11272719 | 0.77 | ITGB1 (0.45) | ITGB1ITGA4ITGB7HTTSMN1; SMN2 | |
| SCHEMBL11277938 | 0.75 | PTGES (0.52) | ITGB1ITGA4ITGB7HTTSMN1; SMN2 | |
| SCHEMBL11278294 | 0.74 | CNR2 (0.49) | ITGB1ITGA4ITGB7SMN1; SMN2NPSR1 | |
| SCHEMBL11277269 | 0.73 | NPC1 (0.56) | ITGB1ITGA4ITGB7HTTSMN1; SMN2 | |
| SCHEMBL11267025 | 0.72 | HTT (0.48) | HTTSMN1; SMN2NPSR1ALDH1A1MITF | |
| SCHEMBL11276599 | 0.71 | TLR7 (0.43) | HTTSMN1; SMN2NPSR1ALDH1A1RAB9A | |
| SCHEMBL11279223 | 0.71 | MEN1 (0.48) | ITGB1ITGA4ITGB7NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |