Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126775 | 0.96 | ALDH1A1 (0.40) | KDM4EGAATDP1L3MBTL1TRPV4 | |
| SCHEMBL1127378 | 0.93 | HPGD (0.41) | GAATDP1ALDH1A1HPGDTP53 | |
| SCHEMBL1126904 | 0.86 | PPARG (0.35) | KDM4EGAAALDH1A1KMT2APTGER4 | |
| SCHEMBL1127595 | 0.85 | KDM4E (0.39) | KDM4EGAAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL15161860 | 0.84 | LMNA (0.44) | KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL16588840 | 0.84 | KDM4E (0.39) | KDM4EGAATDP1L3MBTL1TRPV4 | |
| SCHEMBL1126938 | 0.83 | KDM4E (0.43) | KDM4EGAATDP1ALDH1A1KMT2A | |
| SCHEMBL1126982 | 0.82 | TP53 (0.35) | KDM4EGAATDP1ALDH1A1KMT2A | |
| SCHEMBL1127235 | 0.82 | THRB (0.37) | KDM4EGAATDP1ALDH1A1KMT2A | |
| SCHEMBL1127123 | 0.82 | ALDH1A1 (0.40) | GAATDP1ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |