Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533789 | 0.78 | CYP11B2 (0.45) | CYP11B2PTGS2BCL2CYP11B1CYP19A1 | |
| SCHEMBL8892654 | 0.77 | CYP11B2 (0.47) | CYP11B2PTGS2BCL2CYP11B1CYP19A1 | |
| SCHEMBL6949352 | 0.75 | AKR1C2 (0.47) | CYP11B2TSHRHSD17B10MTNR1A | |
| SCHEMBL7305935 | 0.74 | MTNR1A (0.43) | CYP11B2CYP11B1L3MBTL1MTNR1A | |
| SCHEMBL6958705 | 0.73 | CYP11B2 (0.41) | CYP11B2BCL2CYP11B1DRD2DRD3 | |
| SCHEMBL6825414 | 0.73 | CYP11B2 (0.50) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL10395520 | 0.73 | HTR1A (0.45) | CYP11B2PTGS2CYP11B1CYP19A1DRD2 | |
| SCHEMBL11035078 | 0.73 | CYP11B2 (0.51) | CYP11B2PTGS2BCL2CYP11B1CYP19A1 | |
| SCHEMBL8983557 | 0.73 | CYP11B2 (0.51) | CYP11B2PTGS2BCL2CYP11B1CYP19A1 | |
| SCHEMBL8096734 | 0.72 | PPARG (0.42) | CYP11B2PTGS2TSHRHSD17B10MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |