SCHEMBL1128360

SCHEMBL1128360

[CH]1c2ccccc2Oc2cccc(Oc3ccccc3)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 2/20 0.37
LTA4H P09960 1/20 0.37
DPP4 P27487 1/20 0.37
HRH1 P35367 1/20 0.35
CTNNB1 P35222 1/20 0.35
TRPA1 O75762 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
ALDH1A1 P00352 2/20 0.34
RIPK1 Q13546 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 3/20 0.33
KDM1A O60341 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HTR1A P08908 1/20 0.33
SLC6A3 Q01959 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127600 0.79 CA1 (0.43) LMNAKMT2ATSHRTRPA1ALDH1A1
SCHEMBL328869 0.75 NCOA1 (0.40) LMNAKMT2AGAATSHRLTA4H
SCHEMBL30525702 0.72 TSHR (0.44) LMNAKMT2AGAATSHRLTA4H
Diphenylether SCHEMBL9357610 0.70 LTA4H (0.67) KMT2ATSHRLTA4HL3MBTL1MAPT
SCHEMBL367855 0.70 TRPA1 (0.52) LMNAKMT2AGAATRPA1ALDH1A1
SCHEMBL1275953 0.69 MAPK1 (0.37) LMNAKMT2ADPP4TRPA1ALDH1A1
SCHEMBL2514741 0.68 ALDH1A1 (0.44) KMT2AGAATSHRTRPA1ALDH1A1
SCHEMBL1127529 0.68 TRPA1 (0.39) LMNAKMT2ATRPA1ALDH1A1HPGD
SCHEMBL1127657 0.68 TRPA1 (0.39) KMT2ATRPA1ALDH1A1MAPK1MAPT
SCHEMBL1127937 0.68 TRPA1 (0.39) KMT2ATRPA1ALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
CN-113286781-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-08-08 CN disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
CN-116018558-A Negative photosensitive resin composition, pattern forming method and laminated film 三亚普罗股份有限公司 2023-04-25 CN disclosed
EP-3909943-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION San-Apro Ltd. (JP) 2021-11-17 EP disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST LMNA 3096/4885KMT2A 1227/4885GAA 2014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.