Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292287 | 0.82 | MAOA (0.44) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL11296073 | 0.79 | MAOA (0.49) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL10966476 | 0.76 | MAOA (0.39) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL7817822 | 0.68 | CYP1A2 (0.39) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL31284159 | 0.68 | MAOA (0.38) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL11292349 | 0.66 | HTR6 (0.43) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL7461519 | 0.66 | SIRT2 (0.43) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL29281193 | 0.66 | SIRT2 (0.43) | MAOAMAOBSIRT2TP53 | |
| SCHEMBL30018586 | 0.63 | AHR (0.54) | SIRT2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17166654 | 0.63 | AHR (0.54) | SIRT2MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |