Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292349 | 0.81 | HTR6 (0.43) | MAOAMAOBHTR6MAPK1TSHR | |
| SCHEMBL11283989 | 0.76 | MAOA (0.42) | MAOAMAOBHTR6MAPK1TSHR | |
| SCHEMBL11295359 | 0.75 | MAOA (0.38) | MAOAMAOBMAPK1TSHRHTT | |
| SCHEMBL7334850 | 0.71 | TSHR (0.42) | MAOAMAOBMAPK1TSHRHTT | |
| SCHEMBL11284099 | 0.67 | HTR6 (0.38) | MAOAMAOBHTR6MAPK1TSHR | |
| SCHEMBL4166365 | 0.66 | PTGER1 (0.53) | MAOAMAOBCYP1A2MAPTBCHE | |
| SCHEMBL4166982 | 0.63 | PTGER1 (0.55) | MAOAMAOBACHE | |
| SCHEMBL2313299 | 0.61 | LMNA (0.45) | TSHRCYP1A2KDM4EGAALMNA | |
| SCHEMBL11292287 | 0.61 | MAOA (0.44) | MAOAMAOBMAPK1TSHRHTT | |
| SCHEMBL12071472 | 0.60 | FFAR4 (0.38) | MAOAMAOBMAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1985-11-13 | — | — | EP | disclosed |