Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292287 | 0.82 | MAOA (0.44) | MAOAMAOBTSHRHTTMAPK1 | |
| SCHEMBL11283989 | 0.79 | MAOA (0.42) | MAOAMAOBTSHRHTTMAPK1 | |
| SCHEMBL24792108 | 0.68 | ESR1 (0.40) | MAOAMAOBTSHRHTTMAPK1 | |
| SCHEMBL7817822 | 0.68 | CYP1A2 (0.39) | MAOAMAOBTSHRHTTMAPK1 | |
| SCHEMBL31284159 | 0.68 | MAOA (0.38) | MAOAMAOBTSHRHTTMAPK1 | |
| SCHEMBL11292349 | 0.66 | HTR6 (0.43) | MAOAMAOBTSHRHTTMAPK1 | |
| SCHEMBL24790705 | 0.66 | MAOA (0.31) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL25451382 | 0.65 | CYP1B1 (0.50) | MAOAMAOBALDH1A1MAPTCYP1A2 | |
| SCHEMBL10099058 | 0.64 | CYP1A2 (0.64) | MAOATSHRHTTALDH1A1MAPT | |
| SCHEMBL19803043 | 0.64 | LOXL2 (0.41) | MAOAMAOBMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |