Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296073 | 0.82 | MAOA (0.49) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL11283989 | 0.82 | MAOA (0.42) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL11292349 | 0.78 | HTR6 (0.43) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL11284099 | 0.73 | HTR6 (0.38) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL7817822 | 0.70 | CYP1A2 (0.39) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL31284159 | 0.70 | MAOA (0.38) | MAOAMAOBTSHRMAPK1HTT | |
| SCHEMBL15781372 | 0.66 | CYP1A2 (0.62) | MAOAACHEGRIN1GRIN2ABCHE | |
| SCHEMBL11408384 | 0.62 | HSD17B10 (0.47) | MAOAMAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16597029 | 0.62 | PIM1 (0.44) | TSHRNQO1MAPTHPGDCSNK2A2 | |
| SCHEMBL10966476 | 0.61 | MAOA (0.39) | MAOAMAOBTSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |