Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284099 | 0.84 | HTR6 (0.38) | HTR6MAOAMAOBMAPK1TSHR | |
| SCHEMBL10966476 | 0.81 | MAOA (0.39) | HTR6MAOAMAOBMAPK1TSHR | |
| SCHEMBL11292287 | 0.78 | MAOA (0.44) | MAOAMAOBMAPK1TSHRHTT | |
| SCHEMBL26625828 | 0.69 | ALDH1A1 (0.34) | CYP1A2MAPTLMNACYP2D6CYP2C9 | |
| SCHEMBL10324027 | 0.69 | ESR2 (0.40) | HTR6 | |
| SCHEMBL11283989 | 0.66 | MAOA (0.42) | HTR6MAOAMAOBMAPK1TSHR | |
| SCHEMBL11296073 | 0.66 | MAOA (0.49) | MAOAMAOBMAPK1TSHRHTT | |
| SCHEMBL11332298 | 0.63 | HTR6 (0.47) | HTR6MAOAMAOBMAPK1TSHR | |
| SCHEMBL19123587 | 0.61 | ALDH1A1 (0.33) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL7817822 | 0.61 | CYP1A2 (0.39) | MAOAMAOBMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |