Biphenyl

Biphenyl

SCHEMBL1577458

C1CCC(C2CCCCC2)CC1.Cc1ccccc1C(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.57
RAB9A P51151 1/20 0.57
MYC P01106 1/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HSD17B10 Q99714 1/20 0.47
P2RX7 Q99572 2/20 0.46
ABCC1 P33527 2/20 0.46
ALOX15 P16050 1/20 0.45
KMT2A Q03164 2/20 0.45
HTT P42858 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
TP53 P04637 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluic Acid SCHEMBL28260250 0.91 ALDH1A1 (0.52) NPC1RAB9AMYCALDH1A1HPGD
Toluic Acid SCHEMBL551745 0.89 ALDH1A1 (0.57) NPC1RAB9AMYCALDH1A1HPGD
Biphenyl SCHEMBL8525491 0.87 ALDH1A1 (0.61) NPC1RAB9AALDH1A1HPGDKDM4E
Toluic Acid SCHEMBL28867109 0.83 ALDH1A1 (0.52) NPC1RAB9AMYCALDH1A1HPGD
Toluic Acid SCHEMBL29414127 0.82 ALDH1A1 (0.65) MYCALDH1A1HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6571818 0.82 ALDH1A1 (0.65) MYCALDH1A1HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL4152 0.82 ALDH1A1 (0.65) MYCALDH1A1HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL28037745 0.82 ALDH1A1 (0.65) MYCALDH1A1HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL148201 0.82 ALDH1A1 (0.65) MYCALDH1A1HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL4730975 0.80 ALDH1A1 (0.62) MYCALDH1A1HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2308910-B1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2017-03-01 EP disclosed
US-8999523-B2 Compound containing 1,3-diene structure and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-07 US disclosed
US-8993124-B2 Polymer compound comprising aryl repeating units with crosslinking pendent groups and light-emitting element using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-31 US disclosed
EP-2311893-B1 COMPOUND CONTAINING 1,3-DIENE STRUCTURE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL CO (JP) 2014-09-24 EP disclosed
US-20110127517-A1 COMPOUND CONTAINING 1,3-DIENE STRUCTURE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-02 US disclosed
US-20110127516-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2011-06-02 US disclosed
EP-2311893-A1 COMPOUND CONTAINING 1,3-DIENE STRUCTURE AND METHOD FOR PRODUCING SAME Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2308910-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2011-04-13 EP disclosed
US-20100301310-A1 POLYMER AND POLYMERIC LUMINESCENT ELEMENT EMPLOYING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110127516-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME RER1, NAP1L1, CRY1 NPC1 3715/4885RAB9A 3258/4885MYC 3599/4885
US-20110127517-A1 COMPOUND CONTAINING 1,3-DIENE STRUCTURE AND METHOD FOR PRODUCING SAME KCNMA1, KCNA1, KCNJ11 NPC1 1190/4885RAB9A 2699/4885MYC 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.