Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290070 | 0.82 | HSD17B10 (0.64) | HSD17B10SMN1; SMN2HPGDKDM4ETNKS | |
| SCHEMBL11278787 | 0.80 | SMN1; SMN2 (0.49) | HSD17B10SMN1; SMN2HPGDKDM4ETNKS | |
| SCHEMBL11283262 | 0.79 | KMT2A (0.50) | HPGDKDM4EALDH1A1ACHEHTR3A | |
| SCHEMBL11284725 | 0.78 | NPC1 (0.58) | HSD17B10SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL11278102 | 0.77 | LMNA (0.56) | HSD17B10SMN1; SMN2KDM4ETNKSTNKS2 | |
| SCHEMBL11282521 | 0.76 | HTR3A (0.55) | HSD17B10SMN1; SMN2HPGDKDM4EADRB1 | |
| SCHEMBL11285567 | 0.75 | KDM4E (0.41) | HSD17B10SMN1; SMN2GBA1HPGDKDM4E | |
| SCHEMBL11282866 | 0.75 | GBA1 (0.55) | HSD17B10SMN1; SMN2GBA1HPGDKDM4E | |
| SCHEMBL11287133 | 0.75 | ALDH1A1 (0.50) | HSD17B10SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL11282875 | 0.74 | LMNA (0.58) | HSD17B10SMN1; SMN2HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |