Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280679 | 0.85 | ADRB2 (0.39) | MAPTADRB2ADRB1ADRB3RXFP1 | |
| SCHEMBL11288225 | 0.83 | ALOX15 (0.36) | MAPTRECQLALOX15RXFP1MGLL | |
| SCHEMBL11288228 | 0.82 | ENPP2 (0.38) | L3MBTL1GAATDP1CNR1CNR2 | |
| SCHEMBL11290216 | 0.77 | PMP22 (0.48) | ADRB2ADRB1ADRB3TDP1LMNA | |
| SCHEMBL11290108 | 0.75 | ALOX15 (0.42) | ADRB2ADRB3ALOX15TOP2ALMNA | |
| SCHEMBL11428882 | 0.74 | CCR5 (0.41) | ADRB2ADRB1ADRB3LMNAHPGD | |
| SCHEMBL11284617 | 0.74 | ALOX15 (0.47) | ALOX15MGLLL3MBTL1GAATDP1 | |
| SCHEMBL11281997 | 0.74 | HIF1A (0.51) | ADRB2ADRB1ADRB3TDP1LMNA | |
| SCHEMBL11283530 | 0.72 | ADRB2 (0.52) | MAPTADRB2ADRB1ADRB3RXFP1 | |
| SCHEMBL11285938 | 0.71 | PMP22 (0.47) | ADRB2ADRB1ADRB3TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |