Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11286242 | 0.89 | L3MBTL1 (0.44) | KMT2AMAPTL3MBTL1HPGDADRB2 | |
| SCHEMBL11287555 | 0.89 | ADRB2 (0.48) | KMT2AMAPTSMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11287387 | 0.87 | L3MBTL1 (0.51) | KMT2AALOX15MAPTSMN1; SMN2L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL11284569 | 0.85 | L3MBTL1 (0.41) | KMT2AL3MBTL1HPGDADRB2ADRB1 | |
| SCHEMBL11288428 | 0.82 | PKM (0.38) | KMT2AALOX15MAPTSMN1; SMN2CYP1A2 | |
| Ethylbenzene SCHEMBL11288989 | 0.82 | RAB9A (0.48) | KMT2AMAPTSMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11283417 | 0.81 | ALOX15 (0.48) | KMT2AALOX15ALDH1A1ADRB2 | |
| Hydrochloric Acid SCHEMBL11278977 | 0.80 | ALDH1A1 (0.37) | KMT2AALOX15MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL11281887 | 0.80 | CTNNB1 (0.45) | KMT2AMAPTSMN1; SMN2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10896185 | 0.79 | CTNNB1 (0.44) | KMT2AMAPTSMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |