Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | REN | P00797 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128948 | 0.91 | NPC1 (0.64) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL14397817 | 0.86 | REN (0.50) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL2107224 | 0.84 | ALDH1A1 (0.53) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL28824749 | 0.82 | KMT2A (0.57) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL3750325 | 0.82 | POLB (0.59) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL29993293 | 0.81 | LMNA (0.55) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL17732626 | 0.81 | REN (0.71) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL5146531 | 0.81 | LMNA (0.55) | ALDH1A1NPSR1NPC1RAB9AREN | |
| SCHEMBL5146521 | 0.81 | LMNA (0.55) | ALDH1A1NPSR1NPC1RAB9AREN | |
| Malonic Acid SCHEMBL29264759 | 0.80 | HDAC1 (0.68) | ALDH1A1NPSR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015464-A1 | AMIDE ESTER ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-10-17 | — | — | WO | claimed |
| EP-1996602-B1 | NOVEL LACTOSAMINE DERIVATIVES | GLYCOM APS (DK) | 2011-02-16 | — | — | EP | disclosed |
| WO-1991015464-A1 | AMIDE ESTER ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-10-17 | — | — | WO | disclosed |