Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128948 | 0.86 | NPC1 (0.64) | KMT2AMEN1TDP1KDM4EHDAC3 | |
| SCHEMBL1128947 | 0.82 | ALDH1A1 (0.56) | KMT2AMEN1TDP1KDM4EHDAC3 | |
| SCHEMBL2107224 | 0.79 | ALDH1A1 (0.53) | KMT2AMEN1TDP1KDM4EHDAC3 | |
| SCHEMBL10607038 | 0.79 | HPGD (0.59) | KMT2AMEN1TDP1CYP3A4HPGD | |
| SCHEMBL1003508 | 0.78 | HDAC1 (0.71) | KMT2AMEN1TDP1KDM4EMAPT | |
| Bromide SCHEMBL30777152 | 0.77 | LMNA (0.52) | KMT2AMEN1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL10606452 | 0.76 | KMT2A (0.55) | KMT2AMEN1TDP1CYP3A4HPGD | |
| SCHEMBL17732626 | 0.76 | REN (0.71) | CES1HDAC3HDAC1HDAC7HDAC10 | |
| SCHEMBL5146531 | 0.76 | LMNA (0.55) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL29993293 | 0.76 | LMNA (0.55) | KMT2AMEN1TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989035-A | Sulfuryl fluoride promoted reaction method for converting beta-diketone to alkyne | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | disclosed |