Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289567 | 0.89 | ALDH1A1 (0.43) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11284714 | 0.84 | LMNA (0.48) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11428882 | 0.83 | CCR5 (0.41) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11276480 | 0.82 | ADRB2 (0.48) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11289562 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11282047 | 0.80 | CCR5 (0.38) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11280679 | 0.77 | ADRB2 (0.39) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11289468 | 0.77 | ADRB2 (0.67) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Bitolterol SCHEMBL28134 | 0.77 | LMNA (0.54) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Bitolterol SCHEMBL28133 | 0.77 | LMNA (0.54) | ALDH1A1LMNACYP3A4HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |