Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138501 | 0.74 | ADORA3 (0.58) | RAB9AKMT2ANPSR1MAPTNPC1 | |
| SCHEMBL28402665 | 0.73 | HSD17B1 (0.53) | RAB9AKMT2AABCG2NPSR1MAPT | |
| SCHEMBL14265882 | 0.73 | ADORA3 (0.52) | RAB9AKMT2AABCG2MAPTNPC1 | |
| SCHEMBL25739959 | 0.69 | NPC1 (0.59) | RAB9AKMT2AABCG2MAPTNPC1 | |
| SCHEMBL23554055 | 0.68 | VCP (0.57) | RAB9AKMT2AABCG2MAPTNPC1 | |
| SCHEMBL20426104 | 0.67 | ABCG2 (0.55) | RAB9AKMT2AABCG2NPSR1MAPT | |
| SCHEMBL23554151 | 0.67 | MEN1 (0.49) | RAB9AKMT2AABCG2NPSR1MAPT | |
| SCHEMBL23539563 | 0.67 | KIF11 (0.59) | RAB9AKMT2AABCG2MAPTNPC1 | |
| SCHEMBL30041411 | 0.67 | KIF11 (0.59) | RAB9AKMT2AABCG2MAPTNPC1 | |
| SCHEMBL20320387 | 0.66 | ALDH1A1 (0.46) | RAB9AKMT2ANPSR1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065226-A2 | Sulfenamides, process for their preparation, their utilisation as medicines and their preparation | BAYER AG (DE) | 1982-11-24 | — | — | EP | disclosed |