Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663817 | 0.93 | LMNA (0.87) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL7148358 | 0.88 | ALDH1A1 (0.58) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL5359112 | 0.86 | GAA (0.59) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL11256668 | 0.86 | ALDH1A1 (0.57) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL9139821 | 0.85 | ALDH1A1 (1.00) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL9831538 | 0.84 | LMNA (0.71) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL7107070 | 0.82 | LMNA (0.69) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL17367963 | 0.80 | ALDH1A1 (0.87) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL9671967 | 0.80 | ALDH1A1 (0.87) | TSHRHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL8655261 | 0.79 | ALDH1A1 (0.65) | TSHRHSD17B10LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317768-A | A PHENYL DIESTER OF 3,5-DICARBOXY-1,4-DIHYDROPYRIDINE | LABAZ (FR) | 1982-03-02 | — | — | US | disclosed |
| US-4239893-A | STABILIZERS FOR VINYL RESINS | LABAZ (FR) | 1980-12-16 | — | — | US | disclosed |