Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292115 | 0.86 | TSHR (0.74) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL1007130 | 0.86 | ALDH1A1 (0.73) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL10001054 | 0.82 | ALDH1A1 (0.54) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL7148358 | 0.82 | ALDH1A1 (0.58) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL1663817 | 0.81 | LMNA (0.87) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL11256668 | 0.81 | ALDH1A1 (0.57) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL9672168 | 0.80 | ALDH1A1 (0.65) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL10001053 | 0.80 | ALDH1A1 (0.56) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL9797407 | 0.78 | GAA (0.46) | GAATSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL9831160 | 0.78 | KDM4E (0.64) | GAATSHRLMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183039-B2 | 1,4-dihydropyridine-containing IR-sensitive composition and use thereof for the production of imageable elements | EASTMAN KODAK COMPANY (US) | 2007-02-27 | — | — | US | disclosed |
| US-20060154172-A1 | 1-4-Dihydropyridine-containing ir-sensitive composition and use thereof for the production of imageable elements | KODAK REALTY INC. | 2006-07-13 | — | — | US | disclosed |