Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493287 | 0.83 | TRPV6 (0.41) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL363448 | 0.79 | TRPV6 (0.46) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL1722636 | 0.77 | PCSK9 (0.45) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL1660275 | 0.77 | TRPV6 (0.44) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL1756154 | 0.77 | KDM4E (0.47) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL18550249 | 0.76 | TSHR (0.46) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL117263 | 0.76 | ALDH1A1 (0.45) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Hydrochloric Acid SCHEMBL2526776 | 0.76 | KMT2A (0.45) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Benzene SCHEMBL10445518 | 0.76 | ALDH1A1 (0.45) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL1275435 | 0.74 | PCSK9 (0.47) | TRPV6ORAI1ORAI2ORAI3PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117482117-B | ATP-responsive manganese-based bacterial composite material and preparation method and application thereof | 浙江大学 | 2024-06-11 | — | — | CN | claimed |
| CN-117414422-A | PVA-based ROS (reactive oxygen species) responsive composite hydrogel as well as preparation method and application thereof | 华中科技大学同济医学院附属协和医院 | 2024-01-19 | — | — | CN | claimed |
| CN-116854908-A | Cationic polymer, preparation method and application thereof | 中国科学院长春应用化学研究所 | 2023-10-10 | — | — | CN | claimed |
| CN-115466555-B | Preparation method of antibacterial surface functional film layer of neodymium-iron-boron magnet | 浙江中杭新材料科技有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-111423462-B | Tetraphenyl ethylene borate pyridine salt, preparation method and application thereof, and reagent and method for detecting fructose | 河北大学 | 2023-03-31 | — | — | CN | claimed |
| CN-114748637-A | Phenylboronic acid modified nano-crystal drug stabilizing system and preparation method and application thereof | 中国药科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114712520-A | Nanocrystalline drug stabilizing system, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-07-08 | — | — | CN | claimed |
| CN-111423462-A | Tetraphenyl ethylene borate pyridine salt, preparation method and application thereof, and reagent and method for detecting fructose | 河北大学 | 2020-07-17 | — | — | CN | claimed |
| US-12384813-B2 | Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates | MIRECA MEDICINES GMBH (DE) | 2025-08-12 | — | — | US | disclosed |
| CN-117482117-B | ATP-responsive manganese-based bacterial composite material and preparation method and application thereof | 浙江大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-114712520-B | Nanocrystalline drug stabilization system, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | disclosed |
| US-11892401-B2 | Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| CN-117482117-A | ATP-responsive manganese-based bacterial composite material and preparation method and application thereof | 浙江大学 | 2024-02-02 | — | — | CN | disclosed |
| EP-3774951-B1 | BORONIC ACID DERIVATIVES FOR DIOL-SENSING HYDROGELS | THE PROVOST FELLOWS SCHOLARS AND OTHER MEMBERS OF BOARD OF TRINITY COLLEGE DUBLIN (IE) | 2024-01-31 | — | — | EP | disclosed |
| WO-2009151589-A1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009151598-A1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009126691-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC (US) | 2009-10-15 | — | — | WO | disclosed |
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | US | disclosed |
| EP-1613625-A1 | NOVEL FUSED TRIAZOLONES AND THE USES THEREOF | AstraZeneca AB (SE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004081008-A1 | NOVEL FUSED TRIAZOLONES AND THE USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11892401-B2 | Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases | SI, FABP2, FABP6 | TRPV6 261/4885ORAI1 4027/4885ORAI2 4082/4885 |
| US-12384813-B2 | Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates | PRKG1, PRKG2, PRKAG3 | TRPV6 3374/4885ORAI1 2295/4885ORAI2 2665/4885 |
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | TP53, BRCA1, KLK3 | TRPV6 4577/4885ORAI1 4884/4885ORAI2 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.