Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140856 | 0.85 | CRHBP (0.60) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL8810869 | 0.79 | HCAR3 (0.68) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL4301793 | 0.78 | MAPT (0.70) | MAPTGAAHCAR3ALDH1A1KDM4E | |
| SCHEMBL26496466 | 0.78 | ALDH1A1 (0.69) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL10505373 | 0.78 | ALDH1A1 (0.69) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL8962619 | 0.78 | ALDH1A1 (0.69) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL6132129 | 0.78 | ALDH1A1 (0.69) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL9348638 | 0.78 | ALDH1A1 (0.69) | MAPTGAACRHBPCRHR2HCAR3 | |
| SCHEMBL9755054 | 0.77 | MAPT (0.65) | MAPTGAAHCAR3ALDH1A1KDM4E | |
| SCHEMBL4295085 | 0.76 | MAPT (0.63) | MAPTGAAHCAR3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362697-A | Homogeneous specific binding assay test device having copolymer enhancing substance | MILES LABORATORIES, INC. (US) | 1982-12-07 | — | — | US | disclosed |