Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295802 | 0.85 | TDP2 (0.49) | HTR6ADCY10L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL14415474 | 0.70 | TDP2 (0.50) | HTR6TP53L3MBTL1ALDH1A1TDP2 | |
| SCHEMBL3471911 | 0.69 | TDP2 (0.77) | TP53POLBMAPTL3MBTL1MAPK1 | |
| SCHEMBL8345336 | 0.67 | NR1H2 (0.38) | HTR6ADCY10TP53POLBMAPT | |
| SCHEMBL10284909 | 0.67 | HSP90AB1 (0.44) | ADCY10TP53POLBHSP90AB1MAPT | |
| SCHEMBL6963345 | 0.66 | NR1H2 (0.35) | HTR6ADCY10 | |
| SCHEMBL1970510 | 0.65 | L3MBTL1 (0.46) | HTR6HSP90AB1MAPTL3MBTL1MAPK1 | |
| SCHEMBL7635398 | 0.65 | ALDH1A1 (0.39) | HTR6ADCY10TP53POLBMAPT | |
| SCHEMBL8992968 | 0.64 | IDO1 (0.48) | HSP90AB1MAPTALDH1A1 | |
| SCHEMBL9670480 | 0.63 | MAPT (0.58) | MAPTL3MBTL1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065217-A2 | 5-Haloalkyl-1,2,4-triazole and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |