Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210748 | 0.85 | LTA4H (0.41) | SLC6A4SLC6A2SLC6A3LMNAL3MBTL1 | |
| SCHEMBL9340374 | 0.77 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL3643464 | 0.77 | MEN1 (0.47) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL11048069 | 0.77 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL22966254 | 0.74 | HSPB1 (0.47) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL13860118 | 0.73 | HSPB1 (0.42) | SLC6A4SLC6A2SLC6A3HSPB1LMNA | |
| SCHEMBL13857904 | 0.73 | ALDH1A1 (0.48) | SLC6A4HSPB1ALDH1A1PARP10HTR2A | |
| SCHEMBL22874627 | 0.73 | LMNA (0.48) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL22888657 | 0.73 | RAB9A (0.42) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL10891697 | 0.73 | ALDH1A1 (0.51) | HSPB1ALDH1A1LMNAL3MBTL1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001064-B1 | FLUOROSUBSTITUTED PHENOXYBENZYL-OXYCARBONYLDERIVATIVES, -ALCOHOLS AND -HALIDES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |