Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311644 | 0.79 | MAPT (0.47) | MAPTPOLBKDM4ECYP3A4KMT2A | |
| SCHEMBL9163935 | 0.70 | GPR84 (0.32) | MAPT | |
| SCHEMBL496749 | 0.70 | MEN1 (0.48) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL17459255 | 0.70 | KMT2A (0.46) | MAPTSMN1; SMN2POLBKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL28259963 | 0.69 | MEN1 (0.47) | MAPTKDM4ECYP3A4KMT2AMEN1 | |
| SCHEMBL11316961 | 0.68 | POLB (0.42) | LMNAPOLBKDM4ECYP3A4 | |
| SCHEMBL11533469 | 0.67 | ALKBH5 (0.52) | MAPTSMN1; SMN2LMNAKDM4EKMT2A | |
| SCHEMBL497042 | 0.66 | ACP1 (0.44) | TSHR | |
| SCHEMBL11296078 | 0.66 | POLB (0.44) | MAPTSMN1; SMN2POLBKDM4ECYP3A4 | |
| SCHEMBL29581044 | 0.63 | PNMT (0.54) | CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013936-B1 | REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| US-4299764-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4092308-A | 4-Sulphomethyl substituted hydroxypyridone azo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |