Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249497 | 0.81 | PTPN1 (0.50) | LDHAKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL1695233 | 0.79 | ALDH1A1 (0.52) | SIGMAR1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9296111 | 0.78 | CYP2A6 (0.44) | NCEH1SIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1614544 | 0.72 | SIGMAR1 (0.67) | SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL29666490 | 0.72 | SIGMAR1 (0.67) | SIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL3370074 | 0.69 | HSD17B10 (0.59) | WDR5LDHAKMT2AMEN1USP2 | |
| SCHEMBL29223852 | 0.69 | WDR5 (0.59) | NCEH1WDR5LDHAALDH1A1HPGD | |
| SCHEMBL4748549 | 0.69 | CYP2A6 (0.38) | NCEH1SIGMAR1ALDH1A1HSD17B10LMNA | |
| SCHEMBL4124403 | 0.68 | NCEH1 (0.55) | NCEH1WDR5KMT2AMEN1ALDH1A1 | |
| SCHEMBL5245193 | 0.68 | KDM4E (0.46) | NCEH1KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055857-A2 | Potentiation of topical compositions | UNION CARBIDE CORPORATION (US) | 1982-07-14 | — | — | EP | claimed |
| US-20200102281-A1 | FREE RADICAL- AND REACTIVE OXYGEN SPECIES-REACTING COMPOUNDS | DUKE CHRISTOPHER (US) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102281-A1 | FREE RADICAL- AND REACTIVE OXYGEN SPECIES-REACTING COMPOUNDS | ROS1, NOX4, GPX4 | NCEH1 2673/4885WDR5 3627/4885SIGMAR1 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.