Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387219 | 0.87 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL8170428 | 0.77 | MAPT (0.39) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10956122 | 0.76 | ALKBH5 (0.66) | MAPTALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL11620133 | 0.71 | DAO (0.46) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL10400766 | 0.71 | KDM4E (0.33) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9384017 | 0.69 | ALDH1A1 (0.82) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL4700338 | 0.68 | HCAR1 (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11619453 | 0.67 | NOX4 (0.43) | KMT2AMEN1POLBTSHR | |
| SCHEMBL7070074 | 0.67 | ALDH1A1 (0.69) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL3365278 | 0.66 | MAPT (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56065875-A | — | — | None | — | — | JP | disclosed |
| JP-S5665875-A | PYRAZOLONE DERIVATIVE, ITS PREPARATION, AND DESTROYING AGENT FOR NOXIOUS LIVING CREATURE COMPRISING IT | TOKYO ORGAN CHEM IND LTD | 1981-06-03 | — | — | JP | disclosed |