Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579361 | 0.77 | MEN1 (0.44) | ALOX12MEN1MAPTKMT2AKDM4E | |
| SCHEMBL4700341 | 0.72 | ALOX12 (0.48) | HCAR1TLR8ALOX12MEN1MAPT | |
| SCHEMBL30947058 | 0.69 | HCAR1 (0.47) | HCAR1ALOX12MEN1MAPTKMT2A | |
| SCHEMBL30946978 | 0.69 | AKR1B1 (0.35) | HCAR1 | |
| SCHEMBL11301170 | 0.68 | MAPT (0.44) | HCAR1TLR8ALOX12MEN1MAPT | |
| SCHEMBL30947158 | 0.66 | KAT2B (0.38) | HTTCYP11B2ALDH1A1KDM5BPOLB | |
| SCHEMBL10956122 | 0.65 | ALKBH5 (0.66) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5075617 | 0.64 | MGLL (0.59) | TLR8ALOX12MEN1MAPTKMT2A | |
| SCHEMBL8599860 | 0.64 | TLR8 (0.49) | HCAR1TLR8ALOX12MEN1MAPT | |
| SCHEMBL31312968 | 0.64 | CDK4 (0.47) | HCAR1TLR8ALOX12MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974587-B1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEM IND CO (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-6077814-A | LOW PHYTOTOXICITY TO THE CROP PLANTS; SELECTIVE ACTIVITY | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0974587-A1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |